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Nine people who were studied for a grand total of 10 days. That’s far too small a group, studied for too short a time, to claim: “A handful of walnuts may be an effective weight loss tool.” And yet that’s how the Times chose to frame the findings in its lead sentence. The rest of the story made no attempt to walk back the claim or rein it in — not in the slightest. We’ve written extensively on the dangers of drawing any firm conclusions from tiny studies like this one. The coverage becomes even more suspect when we learn that the reported results had almost nothing to do with weight loss. As the Times eventually gets around to explaining, the subjects in the study consumed smoothies — one with real walnuts and a control smoothie with walnut flavoring. The researchers then performed MRI brain scans while the participants looked at pictures of high-fat foods, low-fat foods, and pictures of rocks and trees. They found: … when people looked at pictures of high-fat food, activation in the insula, a part of the brain involved in appetite and impulse control, increased among those who drank the walnut smoothie, but not among placebo drinkers. Maybe it’s interesting for academic researchers to know that a particular part of the brain lights up in response to pictures of chocolate cake over the course of a few days. But that may have little bearing on what will actually happen when people are confronted with real pieces of cake over the course of months or years. The MRI brain scan in this case is a so-called surrogate for what researchers think might happen in the real world. We’ve written extensively on why surrogate markers often don’t tell the whole story.

For the original version including any supplementary images or video, visit https://www.healthnewsreview.org/2017/08/walnuts-for-weight-loss-times-makes-huge-leap-based-on-brain-scans-of-9-people/

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